Chapter 15GCSE (9–1) · AQA, Edexcel, OCR

GCSE Biology Reproduction & DNA questions by topic

18 exam-style questions (90 marks) in three tiers, with Higher-tier questions tagged. Try each one on paper first, then check the model answer and mark scheme.

Chapter 15 notes

18 questions · 90 marks

Showing 18 of 18 questions

Foundation

Recall and simple application

  1. Q1Foundation[4 marks]

    Complete the sentences about reproduction.

    1. (a)Sexual reproduction involves the fusion of male and female __________.[1]
    2. (b)Asexual reproduction produces genetically __________ offspring.[1]
    3. (c)Meiosis produces __________ gametes from one cell.[1]
    4. (d)At fertilisation, the full chromosome number is __________.[1]
  2. Q2Foundation[4 marks]

    Complete the DNA base-pairing table.

    Base pairing
    Strand 1 baseStrand 2 base
    A________
    C________
    ________G
    ________T
    1. (a)Complete all four pairings.[4]
  3. Q3Foundation[4 marks]

    State one advantage and one disadvantage of asexual reproduction.

    1. (a)One advantage.[2]
    2. (b)One disadvantage.[2]
  4. Q4Foundation[2 marks]

    A DNA sample contains 22% guanine.

    1. (a)Calculate the percentage of cytosine.[1]
    2. (b)Calculate the percentage of adenine.[1]
  5. Q14Foundation[4 marks]

    This question is about how organisms reproduce.

    1. (a)What fuses together in sexual reproduction?[1]
    2. (b)What is a clone?[1]
    3. (c)Name the type of cell division that makes gametes.[1]
    4. (d)State one advantage of a population showing variation.[1]
  6. Q15Foundation[4 marks]

    A short section of one DNA strand reads: A – T – C – G. Give the sequence on the complementary strand.

    1. (a)The base paired opposite the first A.[1]
    2. (b)The base paired opposite the T.[1]
    3. (c)The base paired opposite the C.[1]
    4. (d)The full complementary sequence, in order.[1]

Standard

Structured, exam-style

  1. Q5Standard[6 marks]

    Describe meiosis and explain its importance in sexual reproduction.

    1. (a)Describe what meiosis produces.[3]
    2. (b)Explain why fertilisation restores the chromosome number.[2]
    3. (c)State one other thing meiosis contributes.[1]
  2. Q6Standard[6 marks]

    Compare sexual and asexual reproduction, and explain why the malaria parasite uses both.

    1. (a)Give three differences.[3]
    2. (b)Explain the benefit of using both strategies.[3]
  3. Q7Standard[5 marks]

    Describe the structure of DNA.

    1. (a)Describe the overall shape and building blocks.[3]
    2. (b)State the base-pairing rules.[2]
  4. Q8Standard[5 marks]

    A student claims mutations are always caused by radiation and always harmful. Assess this claim.

    1. (a)Assess both parts of the claim.[4]
    2. (b)State the correct summary of mutation effects.[1]
  5. Q16Standard[5 marks]

    A chimpanzee body cell contains 48 chromosomes.

    1. (a)How many chromosomes are in a chimpanzee sperm cell?[1]
    2. (b)Describe what happens during meiosis.[2]
    3. (c)Explain how fertilisation restores the body-cell number.[1]
    4. (d)Explain why meiosis, not mitosis, is needed here.[1]
  6. Q17Standard[6 marks]

    An analysis of a DNA sample shows it contains 18% thymine.

    1. (a)State the percentage of adenine.[1]
    2. (b)State the combined percentage of guanine and cytosine.[1]
    3. (c)Calculate the percentage of guanine.[2]
    4. (d)Explain the base-pairing rule your working relies on.[2]

Challenging

Data, evaluation and explanation

  1. Q9Challenging[6 marks]

    (Higher) Explain how a gene in the nucleus results in a protein in the cytoplasm.

    1. (a)Write a full explanation.[6]
  2. Q10Challenging[6 marks]

    A farmer’s entire asexually propagated banana crop is destroyed by a single fungal disease.

    1. (a)Explain why one disease could destroy the whole crop.[3]
    2. (b)Explain how sexual reproduction could help future crops.[3]
  3. Q11Challenging[6 marks]

    (Higher) A mutation changes one base in the gene for a digestive enzyme. Explain how this could change the person’s ability to digest food.

    1. (a)Write a full causal chain.[6]
  4. Q12Challenging[5 marks]

    A student says: “Gametes are just small body cells.” Explain what is wrong with this statement.

    1. (a)Explain the differences.[5]
  5. Q13Challenging[6 marks]

    Evaluate the statement: “Sexual reproduction is better than asexual reproduction.”

    1. (a)Assess with evidence from both sides and reach a judgement.[6]
  6. Q18Challenging[6 marks]

    The Human Genome Project read the entire human genome.

    1. (a)State what the term genome means.[2]
    2. (b)Describe three ways this knowledge helps medicine.[3]
    3. (c)Give one reason why a patient might decline a genome-based test.[1]

Next step

Sit the practice paper

A 30-mark paper in the style of a GCSE paper, with a separate mark scheme. Give yourself 40 min.

Question paper

Chapter 15 Practice Paper

30 marks · 40 min · 5 pages

10 multiple-choice questions and structured questions with answer lines. Chapter 15: sexual and asexual reproduction with advantages and disadvantages, meiosis and gametes, DNA structure and complementary base pairing, genes and the genome, protein synthesis (Higher), and mutations.

Mark scheme

PRO

Chapter 15 Practice Paper — mark scheme

Answers · Marking points · 3 pages

Model answers with a mark for each creditworthy point — for marking at home or in class.

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