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Chapter 4G2 / G3

Sec 4 Combined Science (Biology) Molecular Genetics topical questions

12 exam-style questions (56 marks) in three tiers. Try each one on paper first, then check the model answer and mark scheme.

Chapter 4 notes

12 questions · 56 marks

Showing 12 of 12 questions

Foundation

Recall and simple application

  1. Q1Foundation[4 marks]

    Complete the sentences: DNA is the ______; a gene is a ______ of DNA coding for one ______; chromosomes are ______ found in the nucleus.

  2. Q2Foundation[3 marks]

    Name the three parts of a DNA nucleotide.

  3. Q3Foundation[2 marks]

    State the complementary base pairing rule.

  4. Q4Foundation[2 marks]

    How many chromosomes are present in a human body cell, and how are they arranged?

Standard

Structured, exam-style

  1. Q5Standard[4 marks]

    A strand of DNA reads A–T–G–C–C–G–T. Write its complementary strand, showing the rule used.

  2. Q6Standard[4 marks]

    Explain the statement: "One gene is one unit of inheritance coding for one polypeptide."

  3. Q7Standard[4 marks]

    A DNA sample contains 22% guanine. Calculate the percentage of each of the other three bases.

  4. Q8Standard[5 marks]

    Describe how DNA's structure suits its role as the information store of the cell.

Challenging

Data, evaluation and explanation

  1. Q9Challenging[6 marks]

    A student writes: "Genes are made of chromosomes, which are made of cells." Identify and correct the errors, stating the true relationships among cells, chromosomes, genes and DNA.

  2. Q10Challenging[7 marks]

    Two DNA samples come from different plants. Sample X has 15% adenine; sample Y has 35% adenine. (a) Give all four base percentages for each. (b) Explain why the two samples can differ so much while the pairing rule stays the same.

  3. Q11Challenging[7 marks]

    Explain the full chain from a base sequence to a working protein, using haemoglobin as your example. Your answer should name DNA, gene, code, polypeptide and protein in order.

  4. Q12Challenging[8 marks]

    A strand reads C–A–T–G–G–C–T–A. (a) Write its complement. (b) State the percentage of thymine in this 8-base section's double-stranded form, showing your reasoning. (c) A base in the middle of the sequence is damaged and cannot pair. Explain, using base pairing, why the partner strand can be used to restore the original sequence.

Next step

Sit the practice paper

A 30-mark paper set out like a school paper, with a separate mark scheme. Give yourself 40 min.

Question paper

Chapter 4 Practice Paper

30 marks · 40 min · 4 pages

5 multiple-choice questions and structured questions with answer lines. Chapter 4 (DNA–gene–chromosome relationships; nucleotide structure; complementary base pairing; one gene, one polypeptide; the genetic code).

Mark scheme

PRO

Chapter 4 Practice Paper — mark scheme

Answers · Marking points · 2 pages

Model answers with a mark for each creditworthy point — for marking at home or in class.

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