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Topic 14 Practice Paper: Inheritance — question paper

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QQ/IGCSE-BIO/T14

IGCSE · Cambridge IGCSE Biology (Extended (Core + Supplement))

Topic 14 Practice Paper

Inheritance

Duration: 40 minutes
Total: 30 marks
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READ THESE INSTRUCTIONS FIRST

  • Answer all questions.
  • Section A contains ten multiple-choice questions. Choose one answer, A, B, C or D, for each.
  • Section B contains structured questions. Write your answers in the spaces provided.
  • The number of marks is given in brackets [ ] at the end of each question or part question.
  • The total mark for this paper is 30.

Original practice material written against the Cambridge IGCSE Biology syllabus. It is not an official Cambridge examination paper. Topic 14: DNA, genes and alleles, protein synthesis, haploid and diploid, mitosis and meiosis, stem cells, monohybrid crosses and Punnett squares, test crosses, codominance, ABO blood groups and sex-linked colour blindness.

For Examiner’s Use
Section A/ 10
Section B/ 20
Total/ 30

Section A: Multiple-choice questions[10 marks]

Choose one answer for each question. Each question is worth 1 mark.

  1. 1

    Chromosomes are made of

    1. ADNA containing genes
    2. Bprotein only
    3. CmRNA copies
    4. Damino acid chains
    ( )
  2. 2

    A haploid nucleus contains

    1. Atwo sets of chromosomes
    2. Ba single set of chromosomes
    3. Cno chromosomes
    4. D23 pairs of chromosomes in humans
    ( )
  3. 3

    Which cells are produced by meiosis?

    1. ASkin cells
    2. BIdentical body cells
    3. CGametes
    4. DStem cells
    ( )
  4. 4

    An organism with genotype Tt is

    1. Ahomozygous and pure-breeding
    2. Bwithout a phenotype
    3. Chomozygous recessive
    4. Dheterozygous and not pure-breeding
    ( )
  5. 5

    In the cross Tt × Tt, the probability of a tt (recessive) offspring is

    1. A1 in 4
    2. B0
    3. C1 in 2
    4. D3 in 4
    ( )
  6. 6

    A tall pea plant is crossed with a short plant (tt). Half the offspring are short. The tall parent was

    1. ATT
    2. BTt
    3. Ctt
    4. Dunable to be deduced
    ( )
  7. 7

    Both alleles contribute to the phenotype in heterozygotes during

    1. Acomplete dominance
    2. Bsex linkage
    3. Ccodominance
    4. Da test cross
    ( )
  8. 8

    The blood group genotype IᴬIᵒ gives phenotype

    1. AO
    2. BAB
    3. CB
    4. DA
    ( )
  9. 9

    Why is red-green colour blindness more common in males?

    1. AMales have one X chromosome, so one recessive allele is expressed
    2. BFathers always pass the allele to sons
    3. CMales lack cones
    4. DThe Y chromosome carries the gene
    ( )
  10. 10

    A woman who is a carrier of colour blindness (X^N X^n) and a colour-blind man (X^n Y) have a daughter. The chance she is colour-blind is

    1. A0%
    2. B50%
    3. C25%
    4. D100%
    ( )

Section B: Structured questions[20 marks]

Answer all questions in the spaces provided.

  1. 11

    DNA controls the activities of cells.

    1. (a)

      Define the terms gene and allele.

      [2]
    2. (b)

      Describe how a protein is made from a gene. (Extended)

      [3]
    3. (c)

      Explain why a muscle cell does not produce digestive enzymes, although it contains the genes for them. (Extended)

      [1]
  2. 12

    In cats, the allele for black fur (B) is dominant to the allele for ginger fur (b). A heterozygous black cat is mated with a ginger cat.

    1. (a)

      State the genotypes of the two parents.

      [2]
    2. (b)

      Complete a Punnett square for the cross.

      [2]
    3. (c)

      Give the expected ratio of black to ginger kittens.

      [1]
    4. (d)

      Explain why a breeder cannot be sure any single kitten’s fur colour will match the expected ratio. (Extended)

      [2]
  3. 13

    Codominance and sex linkage extend simple dominance. (Extended)

    1. (a)

      Define codominance.

      [1]
    2. (b)

      A mother has blood group A (genotype IᴬIᵒ) and a father has blood group B (genotype IᴮIᵒ). Complete a Punnett square and state all possible blood groups of their children.

      [3]
    3. (c)

      Explain why red-green colour blindness, a sex-linked recessive condition, affects more males than females.

      [3]

— End of paper —