Topic 14 Practice Paper: Inheritance — question paper
IGCSE · Cambridge IGCSE Biology (Extended (Core + Supplement))
Topic 14 Practice Paper
Inheritance
READ THESE INSTRUCTIONS FIRST
- Answer all questions.
- Section A contains ten multiple-choice questions. Choose one answer, A, B, C or D, for each.
- Section B contains structured questions. Write your answers in the spaces provided.
- The number of marks is given in brackets [ ] at the end of each question or part question.
- The total mark for this paper is 30.
Original practice material written against the Cambridge IGCSE Biology syllabus. It is not an official Cambridge examination paper. Topic 14: DNA, genes and alleles, protein synthesis, haploid and diploid, mitosis and meiosis, stem cells, monohybrid crosses and Punnett squares, test crosses, codominance, ABO blood groups and sex-linked colour blindness.
| For Examiner’s Use | |
|---|---|
| Section A | / 10 |
| Section B | / 20 |
| Total | / 30 |
Section A: Multiple-choice questions[10 marks]
Choose one answer for each question. Each question is worth 1 mark.
- 1( )
Chromosomes are made of
- ADNA containing genes
- Bprotein only
- CmRNA copies
- Damino acid chains
- 2( )
A haploid nucleus contains
- Atwo sets of chromosomes
- Ba single set of chromosomes
- Cno chromosomes
- D23 pairs of chromosomes in humans
- 3( )
Which cells are produced by meiosis?
- ASkin cells
- BIdentical body cells
- CGametes
- DStem cells
- 4( )
An organism with genotype Tt is
- Ahomozygous and pure-breeding
- Bwithout a phenotype
- Chomozygous recessive
- Dheterozygous and not pure-breeding
- 5( )
In the cross Tt × Tt, the probability of a tt (recessive) offspring is
- A1 in 4
- B0
- C1 in 2
- D3 in 4
- 6( )
A tall pea plant is crossed with a short plant (tt). Half the offspring are short. The tall parent was
- ATT
- BTt
- Ctt
- Dunable to be deduced
- 7( )
Both alleles contribute to the phenotype in heterozygotes during
- Acomplete dominance
- Bsex linkage
- Ccodominance
- Da test cross
- 8( )
The blood group genotype IᴬIᵒ gives phenotype
- AO
- BAB
- CB
- DA
- 9( )
Why is red-green colour blindness more common in males?
- AMales have one X chromosome, so one recessive allele is expressed
- BFathers always pass the allele to sons
- CMales lack cones
- DThe Y chromosome carries the gene
- 10( )
A woman who is a carrier of colour blindness (X^N X^n) and a colour-blind man (X^n Y) have a daughter. The chance she is colour-blind is
- A0%
- B50%
- C25%
- D100%
Section B: Structured questions[20 marks]
Answer all questions in the spaces provided.
- 11
DNA controls the activities of cells.
- (a)
Define the terms gene and allele.
[2] - (b)
Describe how a protein is made from a gene. (Extended)
[3] - (c)
Explain why a muscle cell does not produce digestive enzymes, although it contains the genes for them. (Extended)
[1]
- (a)
- 12
In cats, the allele for black fur (B) is dominant to the allele for ginger fur (b). A heterozygous black cat is mated with a ginger cat.
- (a)
State the genotypes of the two parents.
[2] - (b)
Complete a Punnett square for the cross.
[2] - (c)
Give the expected ratio of black to ginger kittens.
[1] - (d)
Explain why a breeder cannot be sure any single kitten’s fur colour will match the expected ratio. (Extended)
[2]
- (a)
- 13
Codominance and sex linkage extend simple dominance. (Extended)
- (a)
Define codominance.
[1] - (b)
A mother has blood group A (genotype IᴬIᵒ) and a father has blood group B (genotype IᴮIᵒ). Complete a Punnett square and state all possible blood groups of their children.
[3] - (c)
Explain why red-green colour blindness, a sex-linked recessive condition, affects more males than females.
[3]
- (a)
— End of paper —